Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. The Remarkable Heart-Friendy Properties of Avocados. Or, simply look at what the young-adult,T-score based definition of osteoporosis and osteopeniahas done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. Reddit and its partners use cookies and similar technologies to provide you with a better experience. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Hashimoto's disease progresses slowly over the years. Is Drug-Based Medicine a Form of Human Sacrifice? Also this study finds no link with breast cancer, when others have found a link. PLoSone 2011, 11:e27547. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Thank you for bringing it to our attention. millions treated for hypothyroidism at risk for lung cancer. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called 'active ingredient' T4 versus the natural variations in hormone concentrations found in the 'real thing,' which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: Recently T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. Endocrinology 2008, 149:22412250. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. Thyroid dysfunction after immune checkpoint inhibitor treatment in a Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). A distorted idea of human nature is sold when people are treated as "the market. It's possible, for instance, that the reason both sales of Synthroid and the incidence of lung cancer increased is due to an environmental condition that affected both the thyroid and the lungs. The authors did not study whether individuals who took Synthroid actually developed lung cancer later in life. PLoSone 2011, 11:e27547. People read a study and think that someone like, perhaps me, is saying "it Causes lung cancer. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a 'TSH suppressor.' The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. [14] K A Woeber. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . Millions of people who were not only wrongly diagnosed with cancers and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. I'm not saying that there Is no link between Synthroid and lung cancer. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. 1). Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' 2002 Feb ;25(2):106-9. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). J Exp Biol 2010, 213:28992911. A place for patients and relatives. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. Symptoms. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion This discussion has been closed to comments. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. Heart problems. Brit Med J 1978, 1:210212. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. hyperthyroidism. I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. I very much appreciate the information you shared. Keep checking back for the register link to appear. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). She wrote about a product called Thyrtophin PMG. But what can be done for patients who are at low "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Join the Patient & Caregiver Network. Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM. However, they pointed out that the opposite was recently described, and that "hypothyroidism reduces theaggressiveness of some cancers because of the presence of thyroid hormone receptors oncancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness ofcancers."[1]. I had doctor after doctor tell me it was in my head or I was menopausal. Hypothyroidism: symptoms, causes, treatment, medicine, prevention Post by D.ap Tue Feb 21, 2017 6:40 pm "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and . Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. My Endocrinologist was, and continues to be, open about the elevated risk for thyroid cancer due to the multiple. [learn more: Is Drug-Based Medicine a Form of Human Sacrifice?] Brit Med J 1978, 1:210212. You are using an out of date browser. Dr Childs guesses that patients on levothyroxine monotherapy may be more prone to cancer because they might be under-treated. It was the therapist that I went to that referred me to a specialist who ran the correct tests. I have been reading Izabella Wentz. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. [15] [16] There is also the more logical option of support the body's thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Not what people like me are saying.